The Following Agencies and Organizations are Members of the Upper San Pedro Partnership:
- Arizona Department of Environmental Quality
- Arizona Department of Water Resources
- Arizona State Land Department
- Audubon Arizona
- City of Bisbee
- City of Sierra Vista
- City of Tombstone
- Cochise County
- Cochise Water Project, The
- Fort Huachuca
- Friends of the San Pedro River
- National Park Service
- NRCD (Natural Resource Conservation District)
- Nature Conservancy, The
- Southeast AZ Association of Realtors
- Town of Huachuca City
- US Bureau of Land Management
- US Bureau of Reclamation
- US Fish and Wildlife Service
- US Geological Survey
- USDA Agricultural Research Service